Dermatology in practice - 2010


Neil Cox: an appreciation
Barry Monk and Christopher Tidman
pp 3-3
To many readers of this journal, Neil Cox was known only as the author of his editorial pieces, which combined a fine style with erudition and wit. But to dermatologists in the UK, to GPs in the north-west, and to his many grateful patients in his beloved Cumbria, he was far more.
The genetics of psoriasis
Firas Al Niaimi, Richard B Warren and Christopher EM Griffiths
pp 4-6
Psoriasis is a common, chronic, immune-mediated inflammatory skin disorder with a prevalence of 2% in Caucasians. The most common clinical presentation is chronic plaque psoriasis; however, other subtypes, such as guttate and flexural psoriasis, are frequently encountered. Most cases (75%) of chronic plaque psoriasis present before the age of 40 (early-onset or type 1 psoriasis); late-onset cases presenting after the age of 40 years are classified as type 2 psoriasis. Severe forms of the disease can be associated with increased mortality and morbidity.
Sentinel node biopsy in the management of melanoma
Rubeta N Matin and Rino Cerio
pp 8-11
Primary cutaneous melanoma is a skin tumour with an increasing incidence and a significant mortality rate. Lymph node involvement is an indicator of poor prognosis and can be investigated using the technique of sentinel node biopsy (SNB). The ‘sentinel’ lymph node (SLN), identified using dyes and radioactive colloids, is the first lymph-draining node from the site of the tumour. In this article, we discuss the technique of SNB and its role in the management of patients with melanoma.
What you need to know about chemical peels
Anja Weidmann, Robin Stones and Tamara Griffiths
pp 12-14
The pursuit of young-looking, smooth, ‘glowing’ skin has preoccupied humanity for thousands of years. Cosmetics to enhance the appearance have been a common recourse, but many have sought more invasive methods of reversing the evidence of passing years. Chemical peeling, also known as dermapeeling or chemoexfoliation, is the application of a caustic agent to the skin surface to achieve a controlled injury of variable depth. Removal of the roughened surface, evening pigment and subsequent regeneration of the underlying layers can give refreshed, plumpened, luminescent appearance.
Remembering Neil Cox

pp 16-17
Following the death of Dr Neil Cox, Editor of Dermatology in practice (DIP), we received many messages from his colleagues expressing their sadness – but also their appreciation of his work and his achievements – which we would like to share with you here.
Pityriasis versicolor: all your questions answered
Sweta Rai and Ian Coulson
pp 18-22
Pityriasis (tinea) versicolor (PV) is an extremely common skin eruption seen in daily clinical practice. It is a benign, superficial skin infection caused by the Pityrosporum yeast family. Its prevalence is as high as 40% in tropical climates. No precise data are available for its incidence in the UK, but it is thought to be less than 1% in colder climates, with an increase in cases during the hot and humid months of the year.
Anaphylaxis and angioedema: part 2 – management
Gavin P Spickett
pp 24-26
Part 2 of this two-part article discusses the management of anaphylaxis and angioedema. Part 1 (causes and diagnosis) was published in Dermatology in practice 17.3. For obvious reasons (see part 1), much of the management of anaphylaxis has never been evaluated in controlled clinical trials, and treatment is therefore pragmatic.
Dermatology tips for GPs
Barry Monk
pp 28-29
It is said that 25% of new attendances in general practice are for skin disorders. It was, therefore, appropriate that the Royal Society of Medicine (RSM) ran, on 22 September 2009, a conference (Clinical update: Dermatology for general physicians and GPs) that focused on the sort of acute dermatological problems presenting to non-specialists.
Monk's moments: Am I too late?
Barry Monk
pp 31-31
I used to think that I was quite good at managing skin cancer; I have certainly seen enough of it over the years. I have always consulted next door to my plastic surgeon, and we have had an excellent system of asking each others’ opinions on difficult cases. Until very recently, when the lab was moved, our histopathologist worked just round the corner, so we could easily get his opinion as well, and occasionally we even brought him round to see a case before we biopsied it.