Intended for healthcare professionals

Uses of isotretinoin in disorders other than acne

Isotretinoin (13-cis-retinoic acid) is a vitamin A analogue that has been used for many years for the treatment of severe acne vulgaris. It was licensed in the UK in 1983 for the treatment of severe forms of acne (nodular, conglobate and scarring) only. More recently, it has been available in a topical formulation. However, over the years, dermatologists have used it with success in the treatment of a number of different skin conditions, including other acneiform conditions such as rosacea and hidradenitis suppurativa, as well as in disorders of keratinisation, the prevention of photoaging, and the prevention and treatment of skin cancers.
Dermatology in practice 2007; 15(4): 26–28
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