Treating psoriasis over the past 40 years

Progress in medicine, as with evolution, is mostly continuous and generally insidious, but interspersed with occasional, sudden changes, such as those we are currently witnessing in psoriasis with the introduction of the new biologicals. Reflecting on the 40 years or so that I have worked in dermatology, there has been a steady and almost imperceptible transition in our understanding and management of psoriasis, and over this time there must have been as many discarded therapeutic options as there have been theories as to its cause.