Intended for healthcare professionals

The epidemic of allergic contact dermatitis to methylisothiazolinone

Methylisothiazolinone (MI) is a preservative found in many household, personal care and industrial products. In the recent years, there has been an unprecedented increase in sensitisation to MI due to its widespread use in personal care products, resulting in allergic contact dermatitis (ACD). The first case series of MI-related ACD was described in 2010. By 2013, MI had been dubbed the contact allergen of the year, in what has been described as an ACD epidemic caused by MI. In this article we review the history of the epidemic, and clinical presentation and management of MI-induced allergic contact dermatitis.
Dermatology in practice 2016; 22(1): 8–10
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