Intended for healthcare professionals
REVIEW

Pyoderma gangrenosum: an overview

Nusayhah Hudaa Gopee

MBBS, MSc Dermatology Speciality Trainee Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Philip Jeremy Hampton, MBBS

PhD Dermatology Consultant Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Corresponding author: Dr PJ Hampton,

Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne

Pyoderma gangrenosum (PG) is a noninfectious, auto-inflammatory cutaneous disorder which is considered a prototypical neutrophilic dermatosis. Neutrophilic dermatoses are a group of diseases characterised by the accumulation of neutrophils in the skin and in some cases in internal organs.1 Pyoderma gangrenosum is rare with an estimated incidence of 3-10 cases per million people per year.2 The average age of onset is 40 – 60 years with a female predilection.3,4

Dermatology in practice 2021; 27(3): 60–63
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ISSN 0262-5504 (Print) ISSN 2049-8446 (Online)