When I was a medical student, longer ago than I care to remember, you could almost be guaranteed that in finals there would be a question on the complications of surgery for peptic ulceration. Every hospital had a surgeon whose lucrative stock in trade was performing a vagotomy and pyloroplasty, and every surgical take would include at least one case of perforated ulceration of the stomach. Then along came H2 antagonists, and these cases vanished overnight, and the surgeons were left twiddling their thumbs.
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