Intended for healthcare professionals

How we approach blisters on the lower extremities

When approaching blistering disorders, it is essential to know whether or not the lesions in question are actually blisters. Blisters are visible accumulations of fluid within or beneath the epidermis and can be divided into vesicles or bullae, according to size. Vesicles are less than 0.5 cm in diameter, and are often grouped. Bullae are over 0.5 cm and can be multilocular or unilocular.
Dermatology in practice 2005; 13(4): 10–14
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