Intended for healthcare professionals
Case study

Yellow-orange papuloeruptive lesions with haematological malignancy

Clinical presentation
A 16-year-old male was referred with a six-month history of asymptomatic yellow-orange coloured papules affecting the face. Past medical history included common acute lymphoblastic leukaemia (ALL) diagnosed one year previously. He is being treated as per ALL regime B and is currently on Cycle 7 of maintenance chemotherapy, which includes vincristine, methotrexate, prednisolone and mercaptopurine. He is doing very well on this treatment. His past medical history includes depression and systemic candidiasis. Family history includes hyperlipidaemia, but no xanthomas were reported.

Clinical examination (see Figure 1a–c) revealed multiple symmetric, well-demarcated, flat, slightly infiltrated yellow-orange papules on the forehead, eyelids, nose, perioral and preauricular area. No plaques or bruising were noted. Dermoscopic evaluation revealed a reticular pattern of yellow amorphous homogenous structures with overlying branched and linear vessels.

Dermatology in practice 2018; 24(3): 74–75
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