Primary care

Practical management of actinic keratosis in primary care

The term actinic, or solar, keratosis, meaning a thickened scaly growth (keratosis) caused by sunlight, was coined in 1958. The condition presents as areas of abnormal keratinocyte proliferation and differentiation on adult skin,  typically occurring after prolonged periods of exposure to ultraviolet (UV) radiation on sunexposed areas in fair-skinned individuals. Other risk factors for developing actinic keratoses (AKs) include UVB-specific mutations in the p53 gene, increasing age and immunosuppression following organ transplantation or chemotherapy for malignant disease or in those with HIV infection.

Dermatology in practice 2018; 24(1): 4–8
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