Intended for healthcare professionals

A practical guide to squamous cell carcinoma and other non-melanoma skin cancers

Squamous cell carcinoma (SCC) is the second most common skin cancer after basal cell carcinoma (BCC).1 Like BCCs, SCC belongs to the group of non-melanoma skin cancers. SCCs are tumours arising from the epidermal keratinocytes or their appendages. These tumours can either enlarge locally or metastasise. 

As a result of under-reporting in cancer registries, accurate data for SCC in the UK are lacking. In 2014, 131,772 cases of non-melanoma skin cancers were registered in the UK.2 The incidence of SCC is increasing worldwide, including in the UK. A study that examined the rate of SCC between 2003 and 2012 in the East Norfolk and Waveney region showed a 2.8-fold increase over that period, and the authors felt that it was likely that the rate had increased in the rest of the UK as well.3

Dermatology in practice 2018; 24(2): 32–38
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